RegenesisInternational
GD Tone-Up

Photo Boosters · by Simfle Stick Co., Ltd

GD Tone-Up

Black diamond and gold cage for pigmentation and toning

  • Black diamond, gold cage and brightening actives in one solution
  • Activated by a Q-switched or picosecond 1064 nm Nd:YAG
  • Same procedure time as plain laser toning

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  • Protocol training included
  • Supplied by Regenesis

About

GD Tone-Up is a single-use solution of micro-sized black diamond and gold cage particles with tranexamic acid, niacinamide and arbutin, applied before laser toning. Under the 1064 nm beam the diamond is ejected from the skin surface for a gentle micro-dermabrasion, the gold cage converts light to localised heat for collagen remodelling, and the actives work on pigmentation — three effects in the pass the clinic already performs.

  • GD Tone-Up unit
  • Simfle Stick Illuminator — the home-care companion

Treatment possibilities

Indications from the manufacturer's documentation. Each links to the treatment page.

Recommendations

From physicians who use GD Tone-Up in practice.

  • Prof. Firas Al-Niaimi

    London

  • Dermatologist · United Kingdom

    Prof. Firas Al-Niaimi explains why GD Tone-Up has a place in the treatment room.

    London

How to use

GD Tone-Up in the treatment room, step by step.

  1. 01

    Cleanse and protect

    Cleanse thoroughly. Gauze and goggles over the eyes — the solution must not reach them.

  2. 02

    Apply

    Pour one single-use unit into a bowl, mix with a brush and spread over the whole face. Avoid tattooed eyebrows and hairy areas.

  3. 03

    Dry

    Let the layer dry for 2–4 minutes; press with gauze to check it no longer transfers.

  4. 04

    Laser toning

    Manufacturer's standard setting: Q-switched Nd:YAG 1–1.3 J/cm², 8 mm, 10 Hz; picosecond Nd:YAG 0.6–0.65 J/cm², 8 mm, 10 Hz. Skin types IV–V at 1 J/cm². About 4,000 shots in total, the last few hundred to clear residual diamond. Use a smoke evacuator.

  5. 05

    Wipe

    Remove the remaining solution and gold with cold gauze.

  6. 06

    Illuminator

    Apply Simfle Stick Illuminator as the third step, and send it home with the patient to continue between sessions.

  7. 07

    Course

    Every two weeks, five to ten sessions; every three weeks for sensitive skin, never more than four weeks apart.

  • GD Tone-Up in the treatment room: mixing, application and the laser pass · Regenesis

  • How it works: black diamond, gold cage and the actives under the laser · Simfle Stick

Detailed information

Technology, indications and specifications as documented by Simfle Stick Co., Ltd.

GD Tone-Up single-use unit, mixing bowl and brush ready on the tray
Micro-dermabrasion by black diamond
The diamond particles (about 5 µm, manufacturer) absorb the laser energy and are ejected — not shattered as carbon is — taking surrounding keratin with them. No dust, no explosion, and the skin is left smoother rather than rougher.
Collagen remodelling by gold cage
The cage-shaped gold particle (about 5 µm, manufacturer) is designed to convert 1064 nm light into a controlled, localised heat that supports collagen remodelling in the dermis.
Brightening actives
Tranexamic acid, niacinamide and arbutin are carried in the same solution, so the toning pass and the actives work on pigmentation together.
Lasers
Q-switched or picosecond 1064 nm Nd:YAG. A 1064 nm long-pulsed laser in fractional 100 µs mode is also described by the manufacturer, at 10 J/cm² with a 9 mm spot.
On the IMCAS stage
GD Tone-Up was presented by Prof. Firas Al-Niaimi at IMCAS World Congress in Paris in January 2026.
Home care
Illuminator, a cysteamine peel-off cream pack, is the third step of the protocol and the home-care companion between sessions.
Material
Micro-sized black diamond (about 5 µm) and gold cage (about 5 µm) · tranexamic acid, niacinamide, arbutin · alcohol-based
Activated by
Q-switched or picosecond 1064 nm Nd:YAG
Standard setting (manufacturer)
QS 1–1.3 J/cm² · Pico 0.6–0.65 J/cm² · 8 mm · 10 Hz
Drying time
2–4 minutes before the laser
Shots
About 4,000 in total, including a short pass to clear residual diamond
Course
5–10 sessions, every 2 weeks (max 4 weeks apart)
Unit
Single use, one patient per session
Companion
Simfle Stick Illuminator (home care)
Manufacturer
Simfle Stick Co., Ltd, Daegu, South Korea

Cautions

  • Allergy to metal or gold; allergy to alcohol
  • Not on tattooed eyebrows or hairy areas
  • Laser contraindications apply: active infection, keloid tendency, active eczema/psoriasis/dermatitis, photosensitising medication, recent sun or tanning
  • Wait 2–4 weeks after another laser treatment or peel
  • Use a smoke evacuator during the laser pass

Publications

Evidence consists of a single-session pilot study (ten participants, well tolerated) and a two-patient case report. No controlled trial has been published.

  • Evaluation of the efficacy and safety of the 1,064 nm picosecond Nd:YAG laser with a topically applied gold and diamond suspension for facial skin rejuvenation: a pilot study — Dermatologic Therapy, 2022doi:10.1111/dth.15459
  • Use of 1,064 nm Q-switched Nd:YAG laser therapy assisted with diamond particle suspension and gold microparticle application for acne vulgaris and enlarged facial pores — Medical Lasers, 2021

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